DSpace ISS DSpace ISS DSpace ISS
 

DSpace ISS >
01 - Istituto Superiore di Sanità >
6 - Pubblicazioni su serie non edite da ISS >


Title: Differential effects of chylomicron remnants derived from corn oil or palm oil on bile acid synthesis and very low density lipoprotein secretion in cultured rat hepatocytes
Authors: Bravo, Elena
Cantafora, Alfredo
Marinelli, Tiziana
Avella, Michael
Mayes, Peter A.
Botham, Kathleen M
MeSH: Dietary Fats
Issue Date: 1996
Publisher: Elsevier
Citation: Bravo E, Cantafora A, Marinelli T, Avella M, Mayes PA, Botham KM. Differential effects of chylomicron remnants derived from corn oil or palm oil on bile acid synthesis and very low density lipoprotein secretion in cultured rat hepatocytes. Life sciences 1996;59(4):331-337.
ispartof: Life sciences
Language: en
Type: Article
Peer reviewed: yes
Abstract: Da MEDLINE: The effects of chylomicron remnants derived from corn oil (rich in n-6 polyunsaturated fatty acids) and palm oil (rich in long chain saturated fatty acids) on bile acid synthesis and very low density lipoprotein secretion in cultured rat hepatocytes were studied. Incubation of the cells with corn oil remnants led to increased bile acid production, while the secretion of lipid in very low density lipoprotein remained unchanged. In contrast, addition of palm oil remnants to the medium did not affect bile acid synthesis, but resulted in the secretion of cholesterol-rich very low density lipoprotein. These findings show that chylomicron remnants of different fatty acid composition have differential effects on cholesterol metabolism in liver cells, and provide part of the explanation for the hyper- and hypocholesterolaemic effects of saturated and polyunsaturated fatty acids
ISSN: 0024-3205
Appears in Collections:6 - Pubblicazioni su serie non edite da ISS

Files in This Item:

There are no files associated with this item.

SFX Query

 

Valid XHTML 1.0! DSpace ISS  Istituto Superiore di Sanità  - Feedback