DSpace ISS DSpace ISS DSpace ISS

DSpace ISS >
01 - Istituto Superiore di Sanità >
6 - Pubblicazioni su serie non edite da ISS >

Title: Molecular mechanisms underlying the expression of the human HOX-5.1 gene
Authors: Cianetti, Luciano
Di Cristofaro, A.
Zappavigna, Vincenzo
Bottero, Lisabianca
Boccoli, Giovanni
Testa, Ugo
Russo, Giovanni
Boncinelli, Edoardo
Peschle, Cesare
Issue Date: 1990
Publisher: Oxford University Press
Citation: Cianetti L, Di Cristofaro A, Zappavigna V, Bottero L, Boccoli G, Testa U, Russo G, Boncinelli E, Peschle C. Molecular mechanisms underlying the expression of the human HOX-5.1 gene. Nucleic acids research 1990;18(15):4361-4368.
ispartof: Nucleic acids research
Language: en
Type: Article
Peer reviewed: yes
Abstract: Da MEDLINE: The complex mechanisms underlying homeobox genes expression involve regulation at transcriptional, post-transcriptional and translational levels. The multiple transcripts of the human HOX-5.1 gene are expressed differentially in tissue- and stage-specific patterns during embryogenesis, and differentially induced by retinoic acid (RA) in human embryonal carcinoma (EC) NT2/D1 cells. We have sequenced 6.3 Kb of the genomic region containing the HOX-5.1 gene and analyzed its mechanisms of expression. Two alternative promoters underlie the transcription of two classes of HOX-5.1-specific mRNAs. These classes differ in tissue and subcellular distribution, induction by RA, structure of the 5'-UT region and mRNA stability: these features are compatible with a differential function of the two classes of transcripts in embryogenesis
ISSN: 0305-1048
Appears in Collections:6 - Pubblicazioni su serie non edite da ISS

Files in This Item:

There are no files associated with this item.

View Statistics
SFX Query

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! DSpace ISS  Istituto Superiore di Sanità  - Feedback