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Title: Identification of a consistent pattern of mutations in neurovirulent variants derived from the sabin vaccine strain of poliovirus type 2
Authors: Equestre, Michele
Genovese, Domenico
Cavalieri, F.
Fiore, Lucia
Santoro, Rita
Perez Bercoff, Raul
Issue Date: 1991
Publisher: American Society for Microbiology
Citation: Equestre M, Genovese D, Cavalieri F, Fiore L, Santoro R, Perez Bercoff R. Identification of a consistent pattern of mutations in neurovirulent variants derived from the sabin vaccine strain of poliovirus type 2. Journal of virology 1991;65(5):2707-2710.
ispartof: Journal of virology
Language: en
Type: Article
Peer reviewed: yes
Abstract: Da MEDLINE: Complete nucleotide sequencing of the RNAs of two unrelated neurovirulent isolates of Sabin-related poliovirus type 2 revealed that two nucleotides and one amino acid (amino acid 143 in the major capsid protein VP1) consistently departed from the sequences of the nonneurovirulent poliovirus type 2 712 and Sabin vaccine strains. This pattern of mutation appeared to be a feature common to all neurovirulent variants of poliovirus type 2
ISSN: 0022-538X
Appears in Collections:6 - Pubblicazioni su serie non edite da ISS

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